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30-Day Mortality Following Palliative Radiotherapy
Miriam Vázquez1, Manuel Altabas1, Diana C Moreno1
1Department of Radiation Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain.
Frontiers in Oncology
|May 10, 2021
Summary
Thirty-day mortality after palliative radiation therapy was 17.5%. Male gender, poor performance status, and certain cancers were linked to higher mortality, aiding in identifying patients needing supportive care.
Area of Science:
- Oncology
- Radiation Oncology
- Palliative Care
Background:
- 30-day mortality (30-DM) is a key indicator of patient safety in medical treatments.
- Palliative radiation therapy (RT) aims to improve quality of life for cancer patients.
Purpose of the Study:
- To determine the 30-day mortality rate following palliative RT.
- To identify prognostic factors associated with 30-day mortality in this patient group.
Main Methods:
- Retrospective cohort study of 708 patients treated with palliative RT between 2018-2019.
- Data collected included clinical characteristics and treatment details.
- Statistical analysis to identify factors impacting 30-day mortality.
Main Results:
- The 30-day mortality rate was 17.5%.
- Significant factors included male gender, ECOG Performance Status 2-3, visceral metastases, lung/gastrointestinal/urinary tract tumors, and single-dose RT.
- Multivariate analysis identified male gender, ECOG PS 2-3, and lung/gastrointestinal cancers as independent predictors.
Conclusions:
- The observed 30-day mortality aligns with previous research.
- ECOG Performance Status emerged as the strongest predictor of 30-day mortality.
- Identifying high-risk patients can help avoid potentially futile treatments.
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