Related Experiment Video
Updated: Nov 6, 2025
Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
Hydrodissection: A Novel Approach for Safe Core Needle Biopsy of Small High-Risk Subcapsular Thyroid Nodules
Hojat Ebrahiminik1, Hossein Chegeni2, Javad Jalili3
1Department of Interventional Radiology and Radiation, Sciences Research Center, AJA University of Medical Sciences, Tehran, Iran. dr_ebrahiminik@ajaums.ac.ir.
Purpose:
To evaluate the safety and effectiveness of core needle biopsy (CNB) under the assistance of hydrodissection (HDS).
Materials And Methods:
Of 2325 patients requiring biopsy of thyroid lesions, 21 high-risk patients with subcapsular nodules smaller than 10 mm were recruited into this study. All patients underwent HDS with 0.9% saline solution followed by ultrasound (US)-guided CNB with an 18-gauge semi-automated biopsy needle. The separation success rate (SSR) of the HDS, technical success rate (TSR) of CNB, histopathologic success rate (HSR), and complications were assessed.
Results:
Both the SSR of HDS and TSR of CNB were 100% (21/21). The HSR of the thyroid nodules was 85.7% (18/21). No major complications were recorded.
Conclusion:
HDS before CNB can successfully lead to safe biopsy of small subcapsular thyroid nodules.
Level Of Evidence:
Level 4, Case Series.
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