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Evidence of an nN(amide) → π*Ar Interaction in N-Alkyl-N,N'-diacylhydrazines

Jugal Kishore Rai Deka1, Biswajit Sahariah2, Sushil S Sakpal3,4

  • 1Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh 201314, India.

Organic Letters
|May 11, 2021
PubMed

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Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
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