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Updated: Nov 6, 2025

Fecal micro RNA Isolation
Published on: October 28, 2020
Extracellular vesicle-derived miRNA as a novel regulatory system for bi-directional communication in
Liang Zhao1, Yingze Ye2, Lijuan Gu2
1Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Abstract:
The gut-brain-microbiota axis (GBMAx) coordinates bidirectional communication between the gut and brain, and is increasingly recognized as playing a central role in physiology and disease. MicroRNAs are important intracellular components secreted by extracellular vesicles (EVs), which act as vital mediators of intercellular and interspecies communication. This review will present current advances in EV-derived microRNAs and their potential functional link with GBMAx. We propose that EV-derived microRNAs comprise a novel regulatory system for GBMAx, and a potential novel therapeutic target for modifying GBMAx in clinical therapy.
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