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Iatrogenic Retinal Penetration from Intravitreal Injections
Kamal Kishore1,2, Daniel S McGowan2, Kurt A Hanebrink2
1Illinois Retina and Eye Associates, Peoria, Illinois, USA.
Case Reports in Ophthalmology
|May 12, 2021
Summary
Intravitreal (IVT) injections can cause iatrogenic retinal penetration, leading to severe vision loss. Measuring the injection site from the limbus is crucial for safe IVT procedures.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Vascular Eye Disease
Background:
- Intravitreal injections are common treatments for retinal diseases.
- Potential complications, including retinal penetration, require careful consideration.
Observation:
- Two cases of iatrogenic retinal penetration following intravitreal injections are presented.
- Patients experienced vitreous hemorrhage and retinal detachment, respectively.
Findings:
- Retinal holes were identified during vitrectomy in the quadrant of prior intravitreal injections.
- Both patients had pseudophakic eyes and normal axial lengths, with injections performed without site measurement.
Implications:
- Iatrogenic retinal penetration is a serious complication of intravitreal injections.
- Standardizing intravitreal injection technique by measuring from the limbus may prevent such events.

