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Related Experiment Video

Updated: Nov 6, 2025

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
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[Precision medicine in complex diseases].

Erik Melén1, Bo Jacobsson2, Mikael Benson3

  • 1professor, överläkare, institutionen för klinisk forskning och utbildning, Södersjukhuset, Karolinska institutet; Sachsska barn- och ungdomssjukhuset, Stockholm.

Lakartidningen
|May 12, 2021
PubMed
Summary
This summary is machine-generated.

Precision medicine offers new approaches for complex diseases like cardiovascular and inflammatory conditions. By integrating genetic and environmental data, it aims to improve diagnostics and treatments for these multifactorial disorders.

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Area of Science:

  • Genetics and Medicine
  • Complex Disease Research
  • Personalized Healthcare

Background:

  • Complex diseases (allergic, cardiovascular, metabolic, chronic inflammatory) arise from genetic, environmental, and lifestyle factors.
  • Their multifactorial nature complicates diagnosis, monitoring, and treatment strategies.
  • Advances in genetic mapping and omics profiling reveal underlying pathways and determinants.

Purpose of the Study:

  • To review current clinical applications of precision medicine for complex diseases.
  • To outline a future roadmap for implementing precision medicine in clinical practice for these conditions.

Main Methods:

  • Review of existing literature on precision medicine in complex diseases.
  • Clinical perspective on current applications.
  • Analysis of data from genetic determinants and omics profiling.

Main Results:

  • Precision medicine applications are emerging for common complex diseases.
  • Genetic and omics data are crucial for developing these applications.
  • Current applications focus on improving diagnostics and treatment strategies.

Conclusions:

  • Precision medicine holds significant promise for managing complex diseases.
  • Further clinical implementation requires continued research and data integration.
  • A roadmap is needed to guide the integration of precision medicine into routine care for complex diseases.