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The 510(k) Ancestry of Transvaginal Mesh: When the Subject Is Not a Predicate

Jeremy Rosh1, Chaim M Bell2,3, David R Urbach4,5

  • 1Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

JAMA Surgery
|May 12, 2021
PubMed
Abstract

No abstract available in PubMed .

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Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.Y chromosome mutations are called “Y-linked” and only affect males since they alone carry a copy of that chromosome. Mutations to the relatively small Y chromosome can impact male sexual function and secondary sex characteristics. Y-chromosome infertility is a disorder that affects sperm...