Supported Cu(II)-Schiff base: novel heterogeneous catalyst with extremely high activity for eco-friendly, one-pot and
Pezhman Shiri1,2, Ali Mohammad Amani3,4, Jasem Aboonajmi5
1Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran. pezhmanshiri@yahoo.com.
Abstract:
An effective and proficient process for the synthesis of a variety of thioethers via the one-step reaction of benzyl halides, aryl halides, and thiourea is presented. This strategy is a one-pot procedure to achieve a variety of thioethers without the requirement to thiols as starting compounds. A range of thioethers containing electron donating/electron-withdrawing functional groups were obtained with good to excellent yields under mild conditions. Moreover, the nanocatalyst exhibited excellent recyclability for the reaction, making it more sustainable. One-pot and multi-component synthesis, high yields of final products, green reaction media, high activity of nanocatalyst, simple separation of the products and catalyst, and high regioselectivity are several highlights of this method.
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