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Mechanism through Which Retrocyclin Targets Flavivirus Multiplication

Xiaoying Jia1,2, Jiao Guo1,2, Weirong Yuan3

  • 1State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.

Journal of Virology
|May 13, 2021
PubMed
Summary

Retrocyclin-101 effectively inhibits Japanese encephalitis virus and Zika virus infections by targeting viral entry and replication. This novel θ-defensin shows promise as a potential therapeutic for flavivirus diseases.

Keywords:
DE loopNS2B-NS3 proteaseantiviral effectflavivirusretrocyclin-101

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