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Primary breast angiosarcoma resembling a common benign tumor: A case report
Muhammad Alshaar1, Mahmoud Alkhatib1, Samer Sara1,2
1Department of Surgery, Al-Mouwassat University Hospital, Damascus University, Faculty of Medicine, Damascus, Syria.
Annals of Medicine and Surgery (2012)
|May 13, 2021
Summary
Primary breast angiosarcoma (PAB) is a rare cancer that can mimic benign fibroadenomas. This case highlights the importance of considering PAB in young patients with breast masses, even with atypical presentations.
Area of Science:
- Oncology
- Pathology
Background:
- Breast angiosarcoma (PAB) is a rare vascular neoplasm, accounting for approximately 0.05% of all breast cancers.
- Clinically, PAB can present with features similar to benign conditions like hemangioma or pseudoangiomatous hyperplasia.
Observation:
- A 22-year-old woman presented with a mobile, non-tender breast mass that grew to 8x7 cm.
- Initial ultrasonography revealed a well-circumscribed, hypoechoic, lobular mass, mimicking benign lesions.
- Pathological examination confirmed primary breast angiosarcoma after wide excision.
Findings:
- Primary breast angiosarcoma can present as a giant fibroadenoma on physical examination and ultrasound.
- Immunohistochemistry is crucial for definitive diagnosis of PAB, which is often missed in clinical practice.
- Management typically involves mastectomy, potentially with axillary node dissection.
Implications:
- Physicians must maintain a high index of suspicion for PAB in any breast mass, irrespective of patient age or traditional risk factors.
- Further case reports and series are needed to establish optimal diagnostic and management protocols for PAB.
- Early and accurate diagnosis of PAB is essential for effective treatment and patient outcomes.
