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Updated: Nov 5, 2025

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Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
Published on: May 8, 2015
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Co-self-assembly of multiple DNA origami nanostructures in a single pot
Joshua A Johnson1, Vasiliki Kolliopoulos2, Carlos E Castro3
1Biophysics Graduate Program, The Ohio State University, 281 W Lane Ave, Columbus, OH 43210, USA. castro.39@osu.edu.
Abstract:
Simultaneous self-assembly of two distinct DNA origami nanostructures folded with the same scaffold strand was achieved in a single pot. Relative yields were tuned by adjusting concentrations of the competing strands, correlating well with folding kinetics of individual structures. These results can faciliate efficient fabrication of multi-structure systems and materials.
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