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Hodgkin Lymphoma Associated Retinopathy: Report of a Case
Daphné Dedieu1, Emna Bouayed1, Antoine P Brézin1
1Université de Paris, Department of Ophthalmology, Hôpital Cochin, Paris, France.
Purpose:
To report a case of Hodgkin lymphoma (HL) associated retinopathy.
Method:
Single-case, retrospective review of ophthalmological and systemic manifestations.
Results:
A bilateral panuveitis in a 17-year-old Caucasian woman led to the diagnosis of HL. The ocular findings were characterized by anterior uveitis, vitritis, white chorioretinal lesions, papillitis and vasculitis. The diagnosis of nodular sclerosis stage IIA HL was confirmed by a cervical ganglion biopsy. Other causes of uveitis were excluded. The remission of HL was obtained by chemotherapy and the ocular lesions became quiescent, with pigmented chorioretinal scars, predominating along retinal vessels. Recurring visual symptoms one year later led to the diagnosis of the relapse of the HL. The remission of the HL was again obtained by a second line of chemotherapy while ocular symptoms subsided.
Conclusions:
Hodgkin lymphoma may be added to the list of diseases that can occasionally be revealed by ocular paraneoplastic syndromes.
