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Related Experiment Videos

Copytzy Cruz-Cruz1, Sandra Rodríguez-Dozal2, Marlene Cortez-Lugo3

  • 1Laboratorio de fármacos huérfanos, Departamento de Sistemas Biológicos, Universidad Autónoma Metropolitana-Xochimilco. Ciudad de México, México.. copytzycruz@gmail.com.

Salud Publica De Mexico
|May 13, 2021
PubMed
Summary

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This summary is machine-generated.

Detecting SARS-CoV-2 RNA in wastewater is useful for epidemiological surveillance, though no infectious SARS-CoV-2 virus has been found in treated or untreated wastewater yet.

Area of Science:

  • Environmental Science
  • Virology
  • Public Health

Background:

  • Wastewater surveillance is an emerging tool for monitoring infectious diseases.
  • Coronaviruses, including SARS-CoV-2, are shed in human waste.

Purpose of the Study:

  • To review evidence on SARS-CoV-2 and other coronaviruses in wastewater.
  • To assess the potential of wastewater surveillance for epidemiological monitoring.

Main Methods:

  • Rapid review of publications from PubMed and medRxiv (January 2003 - June 2020).
  • Searched for evidence on coronavirus presence and infectivity in wastewater.

Main Results:

  • 29 publications were included in the review.
  • Non-infectious SARS-CoV-2 RNA was detected in various wastewater types and sludge.

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  • Viral RNA levels correlated with COVID-19 case numbers.
  • SARS-CoV-1 and other coronaviruses remained infectious in raw wastewater for up to two days.

    • Conclusions:

    • No evidence of infectious SARS-CoV-2 in wastewater was found in this review.
    • Quantifying SARS-CoV-2 RNA in wastewater is a valuable tool for epidemiological surveillance.