[Correlation of microangiographic and thermographic signs in sarcoma 45]

Thermographic and microangiographic studies on transplantable sarcoma 45 in subcutaneous and intramuscular implantation of tumor cells showed the appearance of "hot" and "cold" foci in the zone of tumor development. In subcutaneous implantation of sarcoma 45 "hot" foci were observed in the 1st week only, then the focal temperature was decreased and a tumor zone acquired the properties of a "cold" focus. In intramuscular tumor implantation the symptom of a "hot" focus was noted during 3 weeks. Angiography showed that the state of the vascular network of a tumor, rearrangement of microcirculation in external and central tumor zones were in some correlation to a site of tumor inoculation. Tumors of the subcutaneous fat were characterized by rapid avascularization with the formation of the "cold" focus symptom. A high degree of tumor vascularization corresponded to "hot" zones, hypovascular tumors--to "cold" zones. "Hot" zones could develop at the expense of arteriovenous anastomoses discharging hot arterial blood into the venous tumor bed passing the capillaries. Direct correlation was established between the state of blood circulation and a thermographic picture.