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Published on: January 17, 2019
Myomectomy during pregnancy: an obstetric overview
Giuseppe Loverro1, Gianluca R Damiani2, Antonio Malvasi3
1Department of Biomedical Sciences and Human Oncology, Gynecologic and Obstetrics Clinic, University of Bari, Bari, Italy.
Symptomatic uterine fibroids (UFs) during pregnancy can be managed with myomectomy, a feasible procedure. However, surgery in pregnancy carries an increased risk of obstetric complications, including miscarriage and fetal demise.
Area of Science:
- Reproductive Medicine
- Obstetrics and Gynecology
- Surgical Management
Background:
- Uterine fibroids (UFs) are common, affecting 20-40% of women and 10% of pregnancies.
- UFs can cause significant complications during gestation.
Purpose of the Study:
- To review evidence on the management and treatment of uterine fibroids during pregnancy.
- To summarize outcomes and complications associated with UF treatment in pregnant individuals.
Main Methods:
- A comprehensive literature review of case reports and series was conducted.
- Data extracted included gestational age at diagnosis and surgery, fibroid size, delivery route, and perinatal outcomes.
- Two clinical cases were incorporated into the analysis.
Main Results:
- Sixty-six articles and 199 patients were analyzed.
- Myomectomy was frequently performed before 20 weeks gestation (76%), often via laparotomy (85%).
- Complications such as miscarriage or fetal demise occurred in 8% of cases.
Conclusions:
- Myomectomy is a viable option for symptomatic uterine fibroids in pregnancy.
- Surgical intervention during pregnancy is linked to a higher risk of obstetric complications.
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