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The LEGATOS technique: A new tissue-validated dynamic contrast-enhanced MRI method for whole-brain, high-spatial

Ka-Loh Li1, Daniel Lewis1,2,3, David J Coope2,3,4

  • 1Division of Informatics, Imaging and Data Sciences, University of Manchester, Manchester, United Kingdom.

Magnetic Resonance in Medicine
|May 15, 2021
PubMed
Summary

A novel dual-temporal resolution (DTR) dynamic contrast-enhanced MRI (DCE-MRI) method, LEGATOS, enhances microvascular parameter accuracy and spatial resolution for whole-brain analysis. This technique improves the discrimination of plasma volume and vascular leakage effects.

Keywords:
accurate kinetic parameter mappingdual-temporal resolution DCE-MRIperfusion and permeabilityspatial and temporal resolution

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