Parasagittal zonal pattern of olivo-nodular projections in rabbit cerebellum

Injection of horseradish peroxidase (HRP) into the nodulus of the rabbit retrogradely labeled cells in 5 subdivisions of the contralateral inferior olive. Localized HRP injections at each of the medial, intermediate and lateral parts of the nodulus revealed 6 longitudinal zones, two zones in each part, projected differentially from the 5 olivary subdivisions: (i) the medial-most zone projected from the beta nucleus, (ii) the lateral zone of the medial part and (iii) the lateral zone of the intermediate part both from the dorsal cap, (iv) the medial zone of the intermediate part from the ventrolateral outgrowth, (v) the medial zone of the lateral part from the dorsomedial cell column, and (vi) the lateral-most zone from the rostrolateral part of the medial accessory olive. A complication is that the zones (v) and (vi) seemed to cover the dorsal lamina of the nodulus, but not the ventral lamina. The lateral part of the ventral nodulus seemed to be projected from the dorsal cap and may therefore be a lateral extension of zone (iv). There was an indication that the rostral-most area of the medial accessory olive also projects to the nodulus, but a specific receptive zone for this projection was unclear. The present results suggest that the small lateral area of the nodulus previously found to be involved in cardiovascular control is projected from the rostrolateral part of the medial accessory olive and/or the dorsomedial cell column.