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Malignant lymphoma with diffuse cardiac involvement and pulmonary stenosis
Hedieh Alimi1,2, Hoorak Poorzand2,3, Amir Hossein Jafarian4
1Cardiovascular Department, Quaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Journal of Cardiology Cases
|May 17, 2021
Summary
This case report highlights a rare instance of T-cell lymphoblastic lymphoma presenting with diffuse cardiac involvement, leading to acquired pulmonary stenosis. Early diagnosis of cardiac lymphoma is vital for effective treatment and improved patient survival.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Cardiac lymphoma, though rare, can present atypically, posing diagnostic challenges.
- Early detection of lymphoma is critical for treatment efficacy and patient prognosis.
Observation:
- A patient presented with dyspnea and a systolic ejection murmur, indicative of cardiac compromise.
- Pericardial biopsy revealed T-cell lymphoblastic lymphoma, an uncommon cause of cardiac masses.
Findings:
- The lymphoma exhibited diffuse cardiac involvement, unlike the typical focal mass presentation.
- The patient's symptoms improved significantly after chemotherapy, with normalized echocardiography findings post-treatment.
Implications:
- This case underscores the importance of considering lymphoma in the differential diagnosis of cardiac conditions, especially with atypical presentations.
- Recognizing unusual patterns of cardiac lymphoma can aid in earlier diagnosis and intervention, potentially improving outcomes.
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