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[Research progress of nanomaterials in osteomyelitis treatment]
1Department of Orthopaedics, Shanghai General Hospital, Shanghai, 200080, P.R.China.
Objective:
To review the related studies on the application of nanomaterials in the treatment of osteomyelitis, and to provide new ideas for the research and clinical treatment of osteomyelitis.
Methods:
The literature about the treatment of osteomyelitis with nanomaterials at home and abroad in recent years was reviewed and analyzed.
Results:
At present, surgical treatment and antibiotic application are the main treatment options for osteomyelitis. But there are many defects such as antibiotic resistance, residual bone defect, and low effective concentration of local drugs. The application of nanomaterials can make up for the above defects. In recent years, nanomaterials play an important role in the treatment of osteomyelitis by filling bone defects, establishing local drug delivery system, and self-antibacterial properties.
Conclusion:
It will provide a new idea and an important research direction for the treatment of osteomyelitis to fully study the related characteristics of nanomaterials and select beneficial materials to make drug delivery system or substitute drugs.
