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Renal Subcapsular Transplantation of 2'-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude Mice
Published on: July 19, 2019
Successful treatment of congenital systemic juvenile xanthogranulomatosis with pulmonary involvement
Eda Ataseven1, Deniz Kizmazoglu2, Haldun Oniz2
1Division of Pediatric Hematology and Oncology, Department of Pediatrics, Ege University School of Medicine, Izmir, Turkey.
Abstract:
Juvenile xanthogranuloma (JXG) is a common form of non-Langerhans cell histiocytosis, which usually presents with spontaneously regressing skin lesions. Systemic involvement is rare and mostly seen in patients with multiple skin nodules. It can spontaneously regress, but sometimes systemic involvement can cause life-threatening symptoms and can be fatal. Herein, we report a case of congenital systemic JXG with multiple skin nodules, soft tissue and pulmonary involvement. She was successfully treated with chemotherapy according to Langerhans cell histiocytosis treatment protocol IV of the Histiocyte Society (LCH-IV).
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