Related Experiment Video
Updated: Nov 5, 2025

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
Published on: August 16, 2021
Family dynamics and adherence to tuberculosis treatment in pediatric patients
Abdeel Jesse Esparza-Rodríguez1, Martha Marcela Espinoza-Oliva1, José Alberto Tlacuilo-Parra2
1Instituto Mexicano del Seguro Social, Centro Médico Nacional de Occidente "Lic. Ignacio García Téllez", Hospital de Pediatría, Servicio de Infectología Pediátrica.
Background:
There are no studies evaluating family dynamics in pediatric population with tuberculosis. Neither treatment adherence has been measured, even though patient non-adherence is a public health problem, especially in chronic infectious diseases.
Objective:
To assess family dynamics and treatment adherence in pediatric patients with pulmonary and extrapulmonary tuberculosis from an Infectious Diseases Service in Mexico.
Material And Methods:
Descriptive cross-sectional study, conducted from May to July 2015, with 17 patients aged eight to fifteen years -old with tuberculosis. Three instruments in Spanish were applied: family dynamics was measured with the Family APGAR questionnaire, adapted for children aged eight years-old and above; treatment adherence was measured with the Haynes-Sackett and the Morisky-Green-Levine tests.
Results:
In 76.4% of cases, extrapulmonary tuberculosis was higher than pulmonary tuberculosis (23.5%); the most common clinical form was ganglion tuberculosis. Family functionality (94.1%) dominated over moderate dysfunction (5.8%) and severe dysfunction (0%). High adherence to antituberculosis treatment was 58.8% more prominent than the moderate one (29.4%) and the low one (11.7%). The rate of patient abandonment was only 5.8%.
Conclusions:
Findings suggest incorporating the evaluation of family dynamics within the medical controls of the antituberculosis treatment, both in the first level of care and in the hospital. This provision may help to promote high treatment adherence.
Related Concept Videos
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

