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Related Concept Videos

Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

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IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
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The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
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Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Angina II: Classification01:27

Angina II: Classification

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Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
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Angina, a symptom of myocardial ischemia, requires a structured nursing management approach to ensure effective care and prevent complications like myocardial infarction. Comprehensive nursing care involves assessing, diagnosing, planning, implementing interventions, and evaluating outcomes, all tailored to the individual patient's needs.Patient AssessmentNursing assessment begins with a detailed subjective evaluation of symptoms, which typically include chest pain or pressure radiating to the...
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Articles linked to this work by shared authors, journal, and citation graph.

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[Answer to the Methodological review of the article "Clinical characteristics related to mortality by COVID-19 in intensive care"].

Revista medica del Instituto Mexicano del Seguro Social·2022
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[Clinical characteristics related to mortality by COVID-19 in intensive care].

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Related Experiment Video

Updated: Nov 5, 2025

Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

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Acute myocardial infarction in a second-level unit.

Josué Israel López-Valdés1, Miguel Solís-Barraza2

  • 1Instituto Mexicano del Seguro Social, Hospital General Regional No. 66, Unidad de Cuidados Intensivos.

Revista Medica Del Instituto Mexicano Del Seguro Social
|May 18, 2021
PubMed
Summary

Fibrinolysis significantly reduced mortality and complications in acute myocardial infarction patients. This treatment also decreased mechanical ventilation needs and intensive care unit length of stay.

Keywords:
AngioplastyMyocardial InfarctionThrombolytic TherapyTime-to-TreatmentRespiration Artificial

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Last Updated: Nov 5, 2025

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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
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Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
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Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

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Area of Science:

  • Cardiology
  • Intensive Care Medicine
  • Emergency Medicine

Background:

  • Acute myocardial infarction (AMI) is a leading cause of ICU admission and mortality.
  • Limited access to reperfusion therapy in some hospitals impacts patient outcomes.
  • This study examines AMI treatment in a second-level hospital setting.

Purpose of the Study:

  • To compare mortality, length of stay, complications, and mechanical ventilation in AMI patients treated with fibrinolysis versus those without.
  • To evaluate the effectiveness of fibrinolysis as a reperfusion strategy for ST-elevation myocardial infarction.

Main Methods:

  • Observational, retrospective, and analytic study design.
  • Inclusion of patients with ST-elevation acute myocardial infarction admitted to the ICU between October 2008 and September 2018.
  • Evaluation of reperfusion strategy, time to treatment, complications, and patient outcomes.

Main Results:

  • Fibrinolysis was administered to 183 out of 244 included patients.
  • Thrombolyzed patients had significantly shorter treatment times (5.9 vs. 20.4 hours).
  • Fibrinolysis was associated with reduced mechanical ventilation (26.2% vs. 52.4%), shorter ICU stay (3.0 vs. 4.6 days), fewer complications, and lower mortality (16.3% vs. 50.8%).

Conclusions:

  • Fibrinolysis significantly decreases the risk of death in acute myocardial infarction patients.
  • This reperfusion therapy reduces the need for mechanical ventilation and shortens ICU length of stay.
  • Fibrinolysis is associated with a lower frequency of both cardiovascular and non-cardiovascular complications.