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Avoiding culture shock with the SARS-CoV-2 spike protein

Benjamin G Hale1

  • 1Institute of Medical Virology, University of Zurich, Zurich, Switzerland.

Elife
|May 18, 2021
PubMed

Abstract:

When culturing SARS-CoV-2 in the laboratory it is vital to avoid deletions in the gene for the spike protein that could affect the interpretation of experiments.

Keywords:
COVID-19SARS-CoV-2airway organoidscell culture adaptationfurin cleavage siteinfectious diseasemicrobiologyserine proteasesvirus

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