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Recurrent gram-negative bacteremia.

J M Mylotte¹, C McDermott

¹Department of Medicine, Veterans Administration Medical Center, Buffalo, New York 14215.

The American Journal of Medicine

|August 1, 1988

Summary

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Recurrent gram-negative bacteremia, often linked to malignancy and urinary tract infections, affects nearly 10% of patients. Risk factors and outcomes were studied in veteran patients.

Area of Science:

Infectious Diseases
Internal Medicine
Critical Care Medicine

Background:

Recurrent gram-negative bacteremia poses a significant clinical challenge.
Understanding risk factors is crucial for effective patient management.

Purpose of the Study:

To identify patients experiencing recurrent gram-negative bacteremia.
To define potential risk factors associated with bacteremia recurrence.

Main Methods:

Prospective study of 35 patients with 74 gram-negative bacteremia episodes.
Data collected included patient demographics, underlying diseases, infection focus, and outcomes.

Main Results:

Recurrent bacteremia occurred in nearly 10% of patients over 37 months.

Related Experiment Videos

Common focus: urinary tract (50%); common organism: Escherichia coli.

Malignancy was a frequent underlying condition; 17% mortality, often with respiratory focus.

Conclusions:

Recurrent gram-negative bacteremia in veterans is associated with underlying malignancy and urinary tract infections.
Mortality rates are comparable to non-recurrent cases.
Identifying recurrence risk factors is vital for targeted interventions.