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Optic atrophy in children.

M X Repka1, N R Miller

  • 1Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

American Journal of Ophthalmology
|August 15, 1988
PubMed
Summary
This summary is machine-generated.

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Tumors, primarily optic pathway gliomas, are the most frequent cause of childhood optic atrophy. Inflammation and trauma are also significant causes, highlighting the need for thorough investigation in affected children.

Area of Science:

  • Pediatric Ophthalmology
  • Neurology
  • Oncology

Background:

  • Optic atrophy is a significant cause of vision loss in children.
  • Identifying the etiology of optic atrophy is crucial for appropriate management and prognosis.

Purpose of the Study:

  • To determine the causes of optic atrophy in a pediatric population.
  • To analyze the frequency and types of underlying pathologies.

Main Methods:

  • Retrospective review of medical records for 218 children diagnosed with optic atrophy between 1978 and 1987.
  • Categorization of causes including tumors, inflammation, and trauma.

Main Results:

  • A cause was identified in 89% of cases.
  • Tumors were the most frequent cause (29%), with gliomas of the anterior visual pathway being the most common (12% overall).

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  • Inflammation (17%) and trauma (11%) were the second and third most common causes, respectively.

    • Conclusions:

    • Tumors, particularly optic gliomas, are a leading cause of pediatric optic atrophy.
    • Optic atrophy in infancy can be associated with serious conditions like brain tumors.
    • Comprehensive etiological workup is essential for all children diagnosed with optic atrophy.