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Related Experiment Videos

Suramin keratopathy.

E J Holland1, C A Stein, A G Palestine

  • 1Department of Ophthalmology, University of Minnesota, Minneapolis 55455.

American Journal of Ophthalmology
|August 15, 1988
PubMed
Summary
This summary is machine-generated.

High-dose intravenous suramin, used for adrenocortical carcinoma, caused vortex keratopathy in patients. This drug-induced condition presents as corneal and lens changes, resembling lipid storage diseases.

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Area of Science:

  • Ophthalmology
  • Oncology
  • Pharmacology

Background:

  • Adrenocortical carcinoma is a rare cancer.
  • Suramin is an antiparasitic drug with potential anticancer applications.
  • High-dose intravenous administration of drugs can lead to specific toxicities.