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Peritoneal Lymphomatosis: The Great Mimicker.
Danial H Shaikh1, Sudharsan Gongati2, Syeda Hafsah Salman2
1Gastroenterology, BronxCare Health System, Bronx, USA.
Cureus
|May 19, 2021
Summary
Peritoneal lymphomatosis (PL), a rare lymphoma spread, can mimic peritoneal carcinomatosis (PC) on scans. Differentiating PL from PC is crucial for appropriate treatment and avoiding unnecessary surgery.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Peritoneal lymphomatosis (PL) is the intraperitoneal spread of lymphoma, a rare condition.
- It often presents with imaging features similar to peritoneal carcinomatosis (PC), a common malignancy spread.
Observation:
- A 58-year-old male presented with abdominal distention and ascites, initially suspected as PC.
- Imaging findings were consistent with peritoneal carcinomatosis.
Findings:
- Peritoneal biopsy confirmed peritoneal lymphomatosis secondary to low-grade follicular lymphoma.
- This highlights the challenge in differentiating PL from PC based solely on imaging.
Implications:
- Accurate differentiation between PL and PC is critical for patient management.
- Prompt diagnosis of PL can guide appropriate chemotherapy, avoiding interventions for PC.

