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Iron status predicts cognitive test performance of primary school children from Kumasi, Ghana
Afua Afreh Mantey1,2, Reginald Adjetey Annan2, Herman Erick Lutterodt3
1Department of Laboratory Technology, Kumasi Technical University, Kumasi, Ghana.
Insights
Good nutrition is vital for school children's cognition. This study found iron status, particularly hemoglobin levels, positively correlated with cognitive performance in Ghanaian children, highlighting the need for interventions against iron deficiency anemia.
Area of Science:
- Pediatric Nutrition
- Cognitive Development
- Public Health
Background:
- School-aged children's nutritional status is critical for cognitive function.
- Assessing the link between nutrition and cognition in Ghanaian school children.
Purpose of the Study:
- To evaluate the relationship between nutritional status and cognitive performance in school-aged children.
- To identify specific nutritional factors influencing cognition in the Kumasi metropolis, Ghana.
Main Methods:
- 389 children from government schools in Kumasi, Ghana participated.
- Data collected included socio-demographics, anthropometrics, blood nutrient levels, and dietary intake (food frequency questionnaire, previous day recall).
- Cognitive function was assessed using the Ravens Colored Progressive Matrix (RCPM).
Main Results:
- Cognitive status did not significantly vary by anthropometric measurements or dietary patterns.
- Anemia prevalence was higher in children scoring below the 40th percentile on the RCPM.
- Hemoglobin and serum ferritin levels showed a weak positive association with RCPM scores.
- Children with lower folate, vitamin B6, iron, and zinc intake had significantly different cognitive test score percentiles.
Conclusions:
- Iron status, particularly hemoglobin, is correlated with cognitive performance in school-aged children.
- Nutritional strategies targeting iron deficiency anemia are essential for improving cognitive outcomes.
- Further research into specific micronutrient impacts on cognition is warranted.
Background:
Good nutritional status of school-aged children is crucial in achieving improved cognition. The objective of this study was to assess the relationship between nutritional status and cognition of school-aged children in the Kumasi metropolis, Ghana.
Methods:
389 children were selected from ten government-owned schools. Socio-demographic and anthropometric data were collected. Blood samples were collected and analyzed for nutrients levels. Dietary intakes were assessed using food frequency questionnaire and previous day's nutrients intake. Cognition test was performed using the Ravens Colored Progressive Matrix (RCPM).
Results:
Mean age of participants was 8.9±1.4 years, mean RCPM score was 17.9±5.4. More girls scored RCPM below the 40th percentile (45.5%) than boys (33.7%), while mother's level of education significantly associated with RCPM percentiles of the children (p = 0.037). Four dietary patterns were generated from food frequency data, and scores of the second pattern, depicting vegetables, non-fruits, bread and cereals, showed a weak negative correlation (r = -0.132, p = 0.026) with previous day's dietary zinc intake. Cognitive status did not vary by anthropometric and dietary patterns. More anemic (54.4%) than non-anemic (33.3%) children were below the 40th RCPM percentile. Mean previous day's intake for folate (p<0.001), vitamin B6 (p = 0.018), iron (p<0.001), and zinc (p = 0.001) differed significantly between the cognitive test score percentiles of the children. Spearman rank correlation showed weak positive associations between RCPM score and hemoglobin (r = 0.246, p = 0.003) and serum ferritin (r = 0.176, p = 0.036). Binary regression analysis showed anemic children (aOR = 0.4; 95%CI = 0.2-0.8, p = 0.014), compared with non-anemic had decreased odds, while boys, compared with girls had increased odds (aOR = 2.0 95%CI = 1.0-4.0, p = 0.035) for scoring above the 50th RCPM percentile.
Conclusions:
Iron status, especially hemoglobin levels, correlated with the cognitive performance of school-aged children in the metropolis. Thus nutritional strategies aimed at reducing iron deficiency anemia are needed.
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