Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethics in Research01:56

Ethics in Research

24.9K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
24.9K
Embryonic Stem Cells00:57

Embryonic Stem Cells

4.2K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
4.2K
Ethical Issues01:27

Ethical Issues

1.5K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
1.5K
Stem Cell Culture01:17

Stem Cell Culture

5.7K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.7K
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

4.8K
Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
4.8K
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

3.1K
Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

LGBTQ+ persons, queer bioethics, and inclusivity in stem cell research and regenerative medicine.

Regenerative medicine·2025
Same author

Crowdfunding for Complementary and Alternative Cancer Treatments in Tijuana, Mexico: Content Analysis.

JMIR cancer·2024
Same author

Regulatory claims made by US businesses engaged in direct-to-consumer marketing of purported stem cell treatments and exosome therapies.

Regenerative medicine·2023
Same author

Safety and efficacy claims made by US businesses marketing purported stem cell treatments and exosome therapies.

Regenerative medicine·2023
Same author

Vaccine related crowdfunding on a 'Freedom Fundraising' platform.

PloS one·2023
Same author

Advertising Alternative Cancer Treatments and Approaches on Meta Social Media Platforms: Content Analysis.

JMIR infodemiology·2023

Related Experiment Video

Updated: Nov 5, 2025

Working with Human Tissues for Translational Cancer Research
07:48

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

10.1K

Ethical issues concerning a pay-to-participate stem cell study.

Leigh Turner1, Jeremy Snyder2

  • 1University of Minnesota, Center for Bioethics, Minneapolis, Minnesota, USA.

Stem Cells Translational Medicine
|May 19, 2021
PubMed
Summary

This critique highlights ethical concerns in pay-to-participate studies, emphasizing the need for financial conflict of interest disclosure in translational medicine research.

Keywords:
clinical trialsethicsmesenchymal stem cells (MSCs)stem cellsumbilical cord

More Related Videos

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
10:16

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

8.0K
Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies
12:38

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Published on: July 19, 2007

6.4K

Related Experiment Videos

Last Updated: Nov 5, 2025

Working with Human Tissues for Translational Cancer Research
07:48

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

10.1K
Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
10:16

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

8.0K
Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies
12:38

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Published on: July 19, 2007

6.4K

Area of Science:

  • Biomedical Ethics
  • Translational Medicine
  • Stem Cell Research

Background:

  • Pay-to-participate studies present ethical challenges regarding financial disclosures.
  • Businesses selling unproven stem cell treatments may influence research integrity.
  • Journal editorial policies mandate transparency in financial conflicts of interest.

Purpose of the Study:

  • To critique a specific pay-to-participate study for non-disclosure of payments.
  • To identify broader ethical and scientific issues in commercial stem cell research.
  • To underscore the responsibility of authors in disclosing financial conflicts.

Main Methods:

  • Critical analysis of a pay-to-participate study.
  • Review of editorial policies on financial disclosure and conflict of interest.
  • Examination of ethical implications in direct-to-consumer stem cell treatments.

Main Results:

  • The study's failure to disclose payments potentially violated journal policies.
  • Broader ethical and scientific concerns were identified in commercial stem cell studies.
  • Non-disclosure of financial conflicts hinders critical assessment of research.

Conclusions:

  • Authors must comply with journal policies and disclose all financial conflicts.
  • Transparency is crucial for contextualizing clinical studies and assessing research.
  • Further investigation into non-compliance with disclosure policies is warranted.