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Updated: Nov 5, 2025

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Published on: June 29, 2021
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Cervical and Thoracic Spondylotic Myelopathies
Ligia V Onofrei1, A Michael Henrie2
1Department of Neurology, University of Utah, Salt Lake City, UT.
Seminars in Neurology
|May 19, 2021
Summary
Degenerative cervical and thoracic spine myelopathies lack standardized treatment. This review covers their epidemiology, diagnosis, natural history, and management, aiding clinical decision-making.
Area of Science:
- Spine Surgery
- Neurology
- Degenerative Spine Disorders
Background:
- Spondylotic myelopathies are common spinal disorders with variable clinical and treatment approaches.
- A lack of standardized management strategies poses challenges in patient care.
Purpose of the Study:
- To provide a comprehensive overview of degenerative cervical and thoracic spine myelopathies.
- To discuss current understanding of epidemiology, pathophysiology, clinical assessment, natural history, and treatment options.
Main Methods:
- Review of current literature on spondylotic myelopathies.
- Discussion of diagnostic modalities including imaging and neurophysiological tools.
- Examination of assessment instruments and differential diagnoses.
Main Results:
- Detailed review of epidemiology, pathophysiology, and natural history.
- Comprehensive analysis of diagnostic tools: imaging, electromyography/nerve conduction studies, evoked potentials.
- Evaluation of assessment scales: JOA score, modified-JOA, Nurick scale, functional tests.
Conclusions:
- Standardized approaches are needed for managing degenerative myelopathies.
- Accurate diagnosis and assessment are crucial for effective treatment planning.
- Differentiating spondylotic from non-spondylotic myelopathies requires careful evaluation.
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