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Updated: Nov 5, 2025

Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia
Published on: March 3, 2023
Peroral endoscopic myotomy: techniques and outcomes
Roman V Petrov1, Romulo A Fajardo2, Charles T Bakhos1
1Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Peroral endoscopic myotomy (POEM) offers a minimally invasive endoscopic approach for achalasia, a neurodegenerative esophageal disorder. This review covers POEM
Area of Science:
- Gastroenterology
- Minimally Invasive Surgery
- Endoscopy
Background:
- Achalasia is a progressive neurodegenerative esophageal disorder impacting motility and lower esophageal sphincter relaxation.
- Impaired swallowing is a primary symptom of achalasia.
- Traditional treatments include open or minimally invasive surgical myotomy.
Purpose of the Study:
- To review the current status of peroral endoscopic myotomy (POEM) for achalasia.
- To discuss the clinical applications and outcomes of the POEM procedure.
- To explore future directions for POEM in managing esophageal motility disorders.
Main Methods:
- Review of existing literature and clinical data on POEM.
- Analysis of POEM's technical aspects and procedural steps.
- Evaluation of patient outcomes and complication rates associated with POEM.
Main Results:
- POEM achieves controlled myotomy via an endoscopic approach, mirroring surgical objectives.
- The procedure is increasingly adopted as a viable alternative to traditional myotomy.
- Early outcomes suggest efficacy in improving esophageal motility and swallowing.
Conclusions:
- POEM represents a significant advancement in the endoscopic management of achalasia.
- Further research is needed to establish long-term outcomes and optimize POEM techniques.
- The procedure holds promise for expanding minimally invasive treatment options for esophageal disorders.
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