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[Clinicophysiological study of multimodality evoked potentials and computed tomographic findings in persistent
Y Nakamura1, M Nakatsukasa, Y Ibata
1Department of Neurosurgery, School of Medicine, Keio University, Tokyo, Japan.
No to Shinkei = Brain and Nerve
|April 1, 1988
Summary
Auditory brainstem response (ABR), somatosensory evoked potential (SSEP), and visual evoked potential (VEP) tests correlate with clinical grading in persistent vegetative state (PVS) patients. CT scans showing brain atrophy are more indicative of PVS severity than ventricular dilation.
Area of Science:
- Neuroscience
- Clinical Neurophysiology
Background:
- Persistent Vegetative State (PVS) diagnosis relies on clinical assessment and neuroimaging.
- Electrophysiological tests like ABR, SSEP, and VEP offer insights into brain function.
Observation:
- Twenty-two PVS patients underwent ABR, SSEP, and VEP testing.
- CT scans assessed for low density areas, ventricular dilatation, and atrophy.
- Evoked responses and CT findings were graded based on severity.
Findings:
- Short latency somatosensory evoked potential (SSEP) and visual evoked potential (VEP) showed better correlation with clinical PVS grades than auditory brainstem response (ABR).
- CT findings of upper brainstem atrophy and abnormal low density areas were more valuable indicators of clinical severity than ventricular dilatation.
- Electrophysiological abnormalities correlated with clinical grading in PVS.
Implications:
- Combined ABR, SSEP, VEP, and CT scan analysis can aid in evaluating PVS lesions.
- These neurophysiological and imaging techniques provide a comprehensive diagnostic approach for PVS.
- This study highlights the utility of multimodal assessment in understanding PVS pathophysiology.