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Related Concept Videos

Minerals01:26

Minerals

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Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
 
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Bone Remodeling01:40

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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A Bivalve Biomineralization Toolbox.

Tejaswi Yarra1,2, Mark Blaxter3, Melody S Clark2

  • 1Ashworth Laboratories, Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom.

Molecular Biology and Evolution
|May 20, 2021
PubMed
Summary
This summary is machine-generated.

Researchers identified 18 new proteins involved in mollusc shell calcification, expanding our understanding of biomineralization. This discovery aids in studying shell evolution and environmental impacts.

Keywords:
Crassostrea gigasMytilus edulisPecten maximusbiomineralizationdamage-repairtranscriptomics

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Area of Science:

  • Biomineralization
  • Marine Biology
  • Evolutionary Biology

Background:

  • Mollusc shell formation involves calcite deposition catalyzed by enzymes and shell matrix proteins (SMPs).
  • Understanding bivalve biomineralization is complex due to diverse shell forms and protein evolution via domain shuffling.
  • A core set of SMPs essential for shell production across species has been identified.

Purpose of the Study:

  • To identify novel proteins involved in bivalve mollusc shell calcification.
  • To define a minimal set of protein domains required for creating solid microstructures from calcium carbonate.
  • To investigate the impact of environmental changes on biomineralization processes.

Main Methods:

  • Analysis of gene expression during shell repair in three bivalve species (Crassostrea gigas, Mytilus edulis, Pecten maximus).
  • Utilized a matched pair design to minimize inter-individual variation.
  • Integrated data with a database of published biomineralization SMPs.

Main Results:

  • Identified 18 new shared proteins likely involved in shell calcification processes.
  • Discovered genes related to ion transport potentially crucial for calcification and acid-base balance.
  • Established a minimal functional protein domain set for producing solid microstructures.

Conclusions:

  • The study expands the repertoire of candidate biomineralization proteins in bivalves.
  • Findings are crucial for understanding molluscan shell evolution and biomimicry.
  • Provides insights into the potential impacts of environmental change on shell formation.