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Endothelial heterogeneity and plasticity.

Coert Margadant1

  • 1Angiogenesis Laboratory, Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Center, Location VUmc, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. c.margadant@amsterdamumc.nl.

Angiogenesis
|May 20, 2021
PubMed
Summary

Endothelial cells exhibit remarkable plasticity and diversity. This special issue explores novel endothelial phenotypes and functions in both health and disease.

Area of Science:

  • Vascular biology and cell biology.

Background:

  • Endothelial cells display significant phenotypic heterogeneity and plasticity.
  • Recent technological advancements have revealed novel endothelial cell phenotypes and functions.

Discussion:

  • This special issue focuses on the heterogeneity and plasticity of endothelial cells.
  • It highlights their roles in both physiological and pathological conditions.

Key Insights:

  • Emerging technologies are crucial for identifying novel endothelial cell characteristics.
  • Understanding endothelial cell diversity is key to advancing vascular biology.

Outlook:

  • Further research into endothelial cell plasticity will uncover new therapeutic targets.
  • Continued exploration of endothelial phenotypes will deepen our understanding of vascular health and disease.

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