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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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Viral tegument proteins restrict cGAS-DNA phase separation to mediate immune evasion

Guangjun Xu1, Chong Liu2, Sheng Zhou3

  • 1CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Molecular Cell
|May 20, 2021
PubMed

Keywords:
ORF52ORF9VP22cGAScGAS-STING pathwayherpesvirushost-pathogen interactionphase separation

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