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Coccidioidomycosis.

Derek J Bays1, George R Thompson2

  • 1Department of Internal Medicine, Division of Infectious Diseases, University of California Davis Medical Center, 4150 V Street, PSSB, Suite G500, Sacramento, CA 95817, USA.

Infectious Disease Clinics of North America
|May 21, 2021
PubMed
Summary
This summary is machine-generated.

Coccidioidomycosis, a fungal respiratory illness, is increasing in endemic areas. Treatment varies from months to lifelong, guided by symptom severity and patient health.

Keywords:
AntifungalsCoccidioidesEndosporeSpheruleTreatmentValley fever

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Area of Science:

  • Mycology
  • Infectious Diseases
  • Epidemiology

Background:

  • Coccidioidomycosis is caused by Coccidioides fungi, endemic to the southwestern US and parts of the Americas.
  • The incidence of this fungal infection is rising.
  • While often self-limiting, it can cause severe disseminated disease.

Purpose of the Study:

  • To review the epidemiology of coccidioidomycosis.
  • To describe the clinical manifestations of the disease.
  • To outline current treatment options for coccidioidomycosis.

Main Methods:

  • Literature review of coccidioidomycosis epidemiology.
  • Analysis of clinical presentation data.
  • Summary of treatment guidelines and outcomes.

Main Results:

  • Coccidioidomycosis incidence is increasing in endemic regions.
  • Disease presentation ranges from mild respiratory illness to severe disseminated forms.
  • Treatment duration varies widely, from months to lifelong antifungal therapy.

Conclusions:

  • Coccidioidomycosis requires careful management due to increasing incidence and potential for dissemination.
  • Treatment decisions are individualized based on clinical factors.
  • Further research may refine therapeutic strategies for this fungal infection.