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Related Concept Videos

Deleterious Substances in Aggregate01:25

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Deleterious substances in aggregates can be detrimental to the quality and durability of concrete. These substances include organic impurities like loam, which interfere with cement hydration and are usually present in the sand. These prevent a good bond between aggregate and cement paste. Organic impurities can be detected using the colorimetric test, where the darkness of a solution after agitation indicates the level of organic content.
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Silica gel column chromatography is a technique for separating compounds using a column packed with silica gel as the stationary phase. This method relies on differences in the polarity of compounds. Based on their polarities, compounds move between the stationary phase (silica gel) and the mobile phase (the solvent), forming discrete bands in the column.
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The alkali-aggregate reaction in concrete involves natural siliceous minerals in aggregates reacting with alkaline hydroxides derived from cement alkalis. This reaction forms an alkali-silica gel that absorbs water, swells, and increases in volume, which is confined by the surrounding cement paste, creating internal pressures that crack and disrupt the concrete. The extent of expansion and damage can be partly attributed to the alkali-silica reaction's osmotic hydraulic pressure and the...
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Unsoundness of Aggregate due to Volume Change01:26

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Related Experiment Video

Updated: Nov 4, 2025

Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica
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[Silica causes difficulties].

S Pointel1, P Gay2, F Forest3

  • 1Pneumologie et oncologie thoracique, CHU de Saint Etienne, Saint Etienne, France.

Revue Des Maladies Respiratoires
|May 23, 2021
PubMed
Summary
This summary is machine-generated.

Silicosis and sarcoidosis are distinct lung diseases that can be difficult to differentiate. A case study highlights the possibility of their simultaneous development, even with silica exposure potentially influencing sarcoidosis.

Keywords:
GranulomatoseGranulomatosisMaladies professionnellesProfessional illnessesSarcoidosisSarcoïdoseSilicaSiliceSilicoseSilicosis

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Area of Science:

  • Pulmonology
  • Occupational Medicine
  • Pathology

Background:

  • Silicosis and sarcoidosis are distinct interstitial lung diseases.
  • Non-invasive imaging like chest CT scans often fail to differentiate between these conditions.
  • Occupational history, specifically silica particle exposure, is a key diagnostic factor.

Observation:

  • A 62-year-old patient presented with dyspnea and cough.
  • Chest CT revealed micronodular peribronchovascular infiltrates and mediastinal lymphadenopathy.
  • Endoscopic biopsies were inconclusive, necessitating a surgical lung biopsy.

Findings:

  • Histological examination of the lung biopsy confirmed lesions consistent with both silicosis and sarcoidosis.
  • This case presents the rare simultaneous occurrence of these two pathologies.
  • Recent research suggests silica exposure may contribute to sarcoidosis development.

Implications:

  • The simultaneous diagnosis of silicosis and sarcoidosis poses diagnostic challenges.
  • Silica exposure's role in sarcoidosis pathogenesis warrants further investigation.
  • This case underscores the importance of thorough histopathological evaluation in complex lung diseases.