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Related Experiment Video

Updated: Nov 4, 2025

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies
12:55

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Published on: November 27, 2013

11.4K

Microfluidics for Drug Development: From Synthesis to Evaluation.

Yuxiao Liu1,2, Lingyu Sun1,2, Hui Zhang1,2

  • 1Department of Rheumatology and Immunology, Institute of Translational Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.

Chemical Reviews
|May 24, 2021
PubMed
Summary

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This summary is machine-generated.

Microfluidics offers a miniaturized and controllable platform for revolutionizing drug development, encompassing synthesis, delivery, and evaluation. This technology enables high-throughput screening and integrated analyses, accelerating the drug discovery process.

Area of Science:

  • Biotechnology
  • Chemical Engineering
  • Pharmaceutical Sciences

Background:

  • Traditional drug development is lengthy, involving complex synthesis, delivery, and evaluation stages.
  • Microfluidics provides a miniaturized, highly controllable environment for biochemical reactions.
  • This technology integrates analytical strategies for efficient screening and evaluation.

Purpose of the Study:

  • To comprehensively review microfluidics-based systems for drug development.
  • To cover the entire process from drug synthesis to drug evaluation.
  • To discuss current challenges and future prospects in the field.

Main Methods:

  • Review of existing literature on microfluidics in drug development.
  • Synthesis of information on microfluidic applications in synthesis, delivery, and evaluation.

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Last Updated: Nov 4, 2025

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  • Analysis of challenges and future trends.

    • Main Results:

    • Microfluidics enables streamlined and efficient drug synthesis.
    • Integrated microfluidic systems facilitate high-throughput drug screening and evaluation.
    • The technology offers enhanced control and reduced reagent consumption.

    Conclusions:

    • Microfluidics presents a revolutionary approach to drug development.
    • Addressing current challenges will further unlock the potential of microfluidic platforms.
    • This review aims to foster interdisciplinary collaboration in microfluidic drug discovery.