Related Experiment Video
Updated: Nov 4, 2025

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Left Main Coronary Artery Compression in Pulmonary Arterial Hypertension: Percutaneous Treatment to Improve Symptoms
Stefan Edginton1, Christine L D'Arsigny1,2, Cathy McLellan1
1Department of Medicine, Queen's University, Kingston, Ontario, Canada.
Abstract:
A 51-year-old woman with pulmonary arterial hypertension presented with progressive chest pain and dyspnea. Computed tomography imaging showed significant enlargement of her main pulmonary artery (PA) and was suggestive of left main coronary artery (LMCA) compression by the PA. The patient underwent percutaneous coronary intervention, which confirmed the diagnosis and a stent was deployed to the LMCA. Three months after the procedure the patient has near resolution of her symptoms. LMCA compression by an enlarged PA is an important cause of chest pain in patients with pulmonary arterial hypertension and can be managed safely and effectively with percutaneous coronary intervention and stenting.
More Related Videos
09:23Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension
Published on: February 11, 2017
09:40Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
Published on: May 13, 2019
Related Concept Videos
Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
Pulmonary Hypertension: Classification and Pathogenesis
There are various classifications for PH, each relating to different underlying causes and also...
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy III: Hypertrophic Cardiomyopathy