Space missions: psychological and psychopathological issues
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Updated: Nov 4, 2025

Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions
Published on: May 23, 2011
Donatella Marazziti1,2, Alessandro Arone1, Tea Ivaldi1
1Department of Clinical and Experimental Medicine University of Pisa, Pisa, Italy.
Abstract:
Exploring space is one of the most attractive goals that humanity ever set, notwithstanding, there are some psychological and psychopathological risks that should be considered. Several studies identified some possible hazards of space travels and related physical and psychological consequences on astronauts. If some psychological reactions are obviously inherent to the characteristics of the spaceships (habitability, confinement, psychological, and interpersonal relationships), other (disturbances of sleep-wake cycle, personality changes, depression, anxiety, apathy, psychosomatic symptoms, neurovestibular problems, alterations in cognitive function, and sensory perception) represent a clear warning of possible central nervous system (CNS) alterations, possibly due to microgravity and cosmic radiation. Such conditions and eventual CNS changes might compromise the success of missions and the ability to cope with unexpected events and may lead to individual and long-term impairments. Therefore, further studies are needed, perhaps, requiring the birth of a novel branch of psychology/psychiatry that should not only consider the risks related to space exploration, but the implementation of targeted strategies to prevent them.
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