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Intraabdominal Schwannomas Single-center experience
Annali Italiani Di Chirurgia
|May 25, 2021
Summary
Intraabdominal schwannomas are rare, benign nerve sheath tumors. Most patients experience good long-term outcomes, emphasizing the need for accurate preoperative diagnosis to avoid aggressive treatments.
Area of Science:
- Oncology
- Surgical Pathology
- Gastroenterology
Background:
- Intraabdominal schwannomas are uncommon neoplasms originating from nerve sheath cells.
- These tumors, though rare, can present with varied clinical symptoms, most commonly abdominal pain.
Purpose of the Study:
- To present clinical experience with intraabdominal schwannomas.
- To analyze demographic, clinical, treatment, and immunohistochemical characteristics of affected patients.
Main Methods:
- Retrospective examination of 7 patients diagnosed with intraabdominal schwannoma between 2011 and 2019.
- Analysis of clinical presentation, tumor location, treatment outcomes, and immunohistochemical markers (S100, Ki67).
Main Results:
- The study included 7 patients (4 female, 3 male) with a mean age of 51.5 years.
- Common symptoms included abdominal pain; tumors were located in the stomach, pelvis, rectum, pancreas, and juxtadrenal space.
- Most patients had favorable outcomes, with 5 disease-free at a mean follow-up of 60 months; complications were infrequent.
Conclusions:
- Intraabdominal schwannomas are rare, often benign tumors, frequently involving the gastrointestinal tract.
- A good long-term prognosis is typical for schwannomas.
- Consider schwannoma in differential diagnosis of abdominal masses; preoperative diagnosis can guide conservative management, avoiding high-morbidity surgery.
