Related Experiment Videos
Synthesis and biological activity of 2-lactonyl penems
H G Capraro1, E Francotte, B Kohler
1Pharmaceutical Research Department, Ciba-Geigy Ltd., Basel, Switzerland.
The Journal of Antibiotics
|June 1, 1988
Abstract:
A series of potent antibacterial agents have been prepared. These agents are penems carrying a lactone ring in the C-2 position. Excellent activity against Gram-positive and Gram-negative organisms--except Pseudomonas aeruginosa--was found.