ST-Elevation Myocardial Infarction due to Acute Thrombosis in an Adolescent With COVID-19
Jessica Persson1, Michael Shorofsky1, Ryan Leahy1
1Division of Cardiology, Departments of Pediatrics.
Insights
A 15-year-old girl experienced ST-elevation myocardial infarction (STEMI) due to coronary thrombosis linked to COVID-19. This case highlights the need to consider myocardial infarction in pediatric COVID-19 patients with heart dysfunction.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Cardiovascular Medicine
Background:
- ST-elevation myocardial infarction (STEMI) is a known complication of COVID-19 in adults.
- STEMI has not been previously reported in pediatric cases of COVID-19.
- Multisystem inflammatory syndrome in children (MIS-C) is a recognized COVID-19-associated condition in children, but this case is distinct.
Observation:
- A 15-year-old female presented with symptoms suggestive of myocardial infarction.
- The patient was diagnosed with acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
- Clinical presentation included chest pain, ST elevation on electrocardiogram, and evidence of myocardial dysfunction.
Findings:
- Coronary angiography revealed acute thrombosis in the coronary arteries.
- The patient was diagnosed with ST-elevation myocardial infarction (STEMI) secondary to coronary thrombosis.
- The STEMI was not associated with multisystem inflammatory syndrome in children (MIS-C).
Implications:
- This case demonstrates that STEMI can occur in children infected with SARS-CoV-2.
- Coronary thrombosis should be considered as a potential cause of STEMI in pediatric COVID-19 patients.
- Clinicians should maintain a high index of suspicion for myocardial infarction in children presenting with cardiac dysfunction during COVID-19 infection.
Abstract:
STEMI can be the presenting diagnosis in adults with COVID-19; presented is a case of a 15-year-old girl with coronary thrombosis-induced STEMI associated with COVID-19. ST-elevation myocardial infarction (MI) is an identified presentation of coronavirus disease 2019 in adults but has not been reported in children. We present a case of a 15-year-old girl with a coronary thrombosis-induced ST-elevation MI in the setting of acute severe acute respiratory syndrome coronavirus 2 infection, not associated with multisystem inflammatory syndrome in children. The patient presented with chest pain, ST elevation, and myocardial dysfunction. Coronary angiography identified thrombosis treated with anticoagulation and antiplatelet therapy. MI must be considered in children who present with coronavirus disease 2019-associated myocardial dysfunction.
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