ST-Elevation Myocardial Infarction due to Acute Thrombosis in an Adolescent With COVID-19

Jessica Persson1, Michael Shorofsky1, Ryan Leahy1

  • 1Division of Cardiology, Departments of Pediatrics.

Pediatrics
|May 26, 2021
PubMed

Insights

A 15-year-old girl experienced ST-elevation myocardial infarction (STEMI) due to coronary thrombosis linked to COVID-19. This case highlights the need to consider myocardial infarction in pediatric COVID-19 patients with heart dysfunction.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Cardiovascular Medicine

Background:

  • ST-elevation myocardial infarction (STEMI) is a known complication of COVID-19 in adults.
  • STEMI has not been previously reported in pediatric cases of COVID-19.
  • Multisystem inflammatory syndrome in children (MIS-C) is a recognized COVID-19-associated condition in children, but this case is distinct.

Observation:

  • A 15-year-old female presented with symptoms suggestive of myocardial infarction.
  • The patient was diagnosed with acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
  • Clinical presentation included chest pain, ST elevation on electrocardiogram, and evidence of myocardial dysfunction.

Findings:

  • Coronary angiography revealed acute thrombosis in the coronary arteries.
  • The patient was diagnosed with ST-elevation myocardial infarction (STEMI) secondary to coronary thrombosis.
  • The STEMI was not associated with multisystem inflammatory syndrome in children (MIS-C).

Implications:

  • This case demonstrates that STEMI can occur in children infected with SARS-CoV-2.
  • Coronary thrombosis should be considered as a potential cause of STEMI in pediatric COVID-19 patients.
  • Clinicians should maintain a high index of suspicion for myocardial infarction in children presenting with cardiac dysfunction during COVID-19 infection.

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