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The incidence of cancer following total hip replacement
W J Gillespie1, C M Frampton, R J Henderson
1Christchurch Hospital, Christchurch School of Medicine, University of Otago, New Zealand.
The Journal of Bone and Joint Surgery. British Volume
|August 1, 1988
Abstract:
We have studied the incidence of tumours at remote sites following total hip replacement: 1,358 individuals have been followed up for 14,286 person-years after operation. In the decade following implantation the incidence of tumours of the lymphatic and haemopoietic systems was significantly greater, and that of cancer of the breast, colon, and rectum, significantly less than expected. Whilst the association might be due in part to an effect of the prosthetic implants, other mechanisms, particularly drug therapy, require consideration.