Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The PhenX Toolkit: Long COVID Collection of Standard Protocols.

Current protocols·2026

Same author

Rare coding variants from ADSP R5 whole-genome sequencing implicate novel genes in Alzheimer's disease.

Research square·2026

Same author

Advancing the science of genomic learning healthcare systems.

Learning health systems·2025

Same author

Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP): A global effort to identify genetic factors in Alzheimer's disease.

Alzheimer's & dementia (New York, N. Y.)·2025

Same author

Longitudinal Assessment of Area of Reticular Pseudodrusen in Eyes with Age-Related Macular Degeneration.

Ophthalmology science·2025

Same author

Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Search research articles

Related Experiment Video

Updated: Nov 4, 2025

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

Published on: October 6, 2023

Using the PhenX Toolkit to Select Standard Measurement Protocols for Your Research Study.

Lisa Ann Cox¹, Stephen Hwang¹, Jonathan Haines²

¹RTI International, Research Triangle Park, North Carolina.

Current Protocols

|May 26, 2021

Summary

This summary is machine-generated.

The PhenX Toolkit offers standardized measurement protocols for phenotypes and exposures to enhance research collaboration and data analysis. It supports study design with compatible data dictionaries and collection worksheets for broader scientific impact.

Keywords:

data collection protocols environmental exposures genome-wide association studies (GWAS)phenotypes standard measures

More Related Videos

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome

Published on: September 20, 2022

Related Experiment Videos

Last Updated: Nov 4, 2025

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

Published on: October 6, 2023

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome

Published on: September 20, 2022

Area of Science:

Biomedical Research
Human Participant Studies
Data Standardization

Background:

The PhenX (consensus measures for Phenotypes and eXposures) initiative aims to standardize measurement protocols.
Standardization facilitates collaborative research and cross-study analysis, increasing the impact of individual studies.
The PhenX Toolkit provides a centralized resource for accessing these standardized protocols.

Purpose of the Study:

To introduce the PhenX Toolkit as a resource for researchers.
To highlight the utility of standardized measurement protocols in human participant studies.
To encourage the adoption of PhenX protocols for improved research reproducibility and data integration.

Main Methods:

The PhenX Toolkit curates high-quality, consensus-based measurement protocols across 29 research domains and 6 specialty collections.
Protocols are recommended by domain expert Working Groups with community input.
The Toolkit offers detailed descriptions, rationales, supporting documentation, and data submission compatibility (e.g., dbGaP, REDCap).

Main Results:

The PhenX Toolkit provides access to a wide array of standardized protocols for phenotypes and exposures.
It includes resources for study design, such as data dictionaries and collection worksheets.
The Toolkit facilitates the identification of studies utilizing PhenX protocols.

Conclusions:

The PhenX Toolkit is a valuable resource for researchers seeking to implement standardized measurement protocols.
Adoption of PhenX protocols can enhance data quality, comparability, and collaborative potential in human studies.
The Toolkit supports robust study design and data management for increased scientific impact.