A case of primary retroperitoneal amyloidoma resected laparoscopically
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Published on: October 6, 2023
Yoshikazu Kuroki1, Kaoru Kimura1, Koji Harimoto2
1Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
Abstract:
Amyloidosis is known as a group of diseases that causes various disorders because of deposition of amyloid protein in various organs. Amyloidosis occurring in the retroperitoneum is a rare disease. We report a 75-year-old male patient presented to our hospital because he was identified with a retroperitoneal mass incidentally by CT. Laparoscopic surgery was performed to resect the tumor. In the histopathological specimen, amyloid was found in the fibrous soft tissue by Congo red staining. This is the first report to document a primary solitary amyloidosis of the retroperitoneum without systemic amyloidosis, which was resected using the laparoscopic approach.
Insights
This report details a rare case of primary solitary amyloidosis in the retroperitoneum, a condition involving amyloid protein deposition. The tumor was successfully resected using minimally invasive laparoscopic surgery.
Area of Science:
- Medicine
- Pathology
- Surgery
Background:
- Amyloidosis encompasses diverse disorders stemming from amyloid protein deposition in organs.
- Retroperitoneal amyloidosis is an exceptionally rare manifestation of this disease group.
Observation:
- A 75-year-old male incidentally discovered to have a retroperitoneal mass via CT scan.
- The mass was surgically resected using a laparoscopic approach.
- Histopathological examination confirmed amyloid deposition in fibrous soft tissue via Congo red staining.
Findings:
- This case represents the first documented instance of primary solitary amyloidosis localized to the retroperitoneum.
- The patient did not exhibit signs of systemic amyloidosis.
Implications:
- This case highlights the possibility of localized retroperitoneal amyloidosis.
- Successful laparoscopic resection offers a minimally invasive treatment option for such rare conditions.
- Further research may elucidate the specific mechanisms and optimal management of primary retroperitoneal amyloidosis.
