Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

473
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
473
Genomics02:02

Genomics

38.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
38.3K
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

114
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
114
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

176
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
176
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

96
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
96
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

547
Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
547

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Results from London Regional Clinical Genetics services over a 5-year period on germline <i>TP53</i> testing in women diagnosed with breast cancer at <30 years.

Journal of medical genetics·2021
Same author

Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics.

Nature genetics·2021
Same author

Quality of care for patients with acute coronary syndromes as a function of hospital revascularization capability: Insights from get with the guidelines-CAD.

Clinical cardiology·2014
Same author

Peripheral artery disease is a coronary heart disease risk equivalent among both men and women: results from a nationwide study.

European journal of preventive cardiology·2014
Same author

Obstructive sleep apnea and diurnal nondipping hemodynamic indices in patients at increased cardiovascular risk.

Journal of hypertension·2013
Same author

The latest research advances in invasive cardiology.

The Journal of invasive cardiology·2013
Same journal

Sex-specific echocardiographic remodeling and prognostic value of left ventricular sphericity, pressure-dimension index, and myocardial work after durable LVAD implantation.

Frontiers in cardiovascular medicine·2026
Same journal

Association of age at menopause with cardiovascular disease and mortality:insights from NHANES and a clinical cohort.

Frontiers in cardiovascular medicine·2026
Same journal

Lipid changes after interleukin-6 blockade in rheumatoid arthritis: beyond cholesterol elevation toward hepatic inflammatory-lipoprotein remodeling.

Frontiers in cardiovascular medicine·2026
Same journal

Ticagrelor plasma concentration, metabolite ratio, and LDH level as independent risk factors for ticagrelor-induced dyspnea in ACS patients.

Frontiers in cardiovascular medicine·2026
Same journal

Mortality trends and disparities in older U.S. adults with atrial fibrillation and COPD: a 1999-2020 CDC WONDER analysis with forecast to 2030.

Frontiers in cardiovascular medicine·2026
Same journal

The effects of combined endurance and resistance exercise training in heart failure: a meta-analysis.

Frontiers in cardiovascular medicine·2026
See all related articles

Related Experiment Video

Updated: Nov 4, 2025

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
09:43

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering

Published on: November 22, 2019

6.5K

Panomics: New Databases for Advancing Cardiology.

Dara Vakili1, Dina Radenkovic2, Shreya Chawla3

  • 1Imperial College School of Medicine, Imperial College London, London, United Kingdom.

Frontiers in Cardiovascular Medicine
|May 27, 2021
PubMed
Summary
This summary is machine-generated.

Panomics, combining multiple omic datasets, offers deep biological insights for personalized medicine. The UK BioBank is a leading resource, but other databases also support specific panomic research needs.

Keywords:
big datacardiologydatabasegenomicsmethylomicspanomicsproteomicssystems biology

More Related Videos

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.7K
Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph
05:32

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph

Published on: February 21, 2025

501

Related Experiment Videos

Last Updated: Nov 4, 2025

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
09:43

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering

Published on: November 22, 2019

6.5K
Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.7K
Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph
05:32

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph

Published on: February 21, 2025

501

Area of Science:

  • Cardiology
  • Systems Biology
  • Personalized Medicine

Background:

  • Cardiology presents challenges in distinguishing disease markers from noise.
  • Panomics integrates diverse omic methods for deeper biological understanding.
  • Systems biology approaches are crucial for personalized medicine development.

Purpose of the Study:

  • To survey omic databases for cardiovascular research.
  • To identify available data types and applications of panomics.
  • To evaluate current and future developments in omics databases.

Main Methods:

  • Systematic search for omic databases.
  • Inclusion criteria: genomic, clinical, and at least one omic dataset.
  • Categorization of databases by omic type (methylomic, transcriptomic, etc.).

Main Results:

  • Identified 104 omic databases; 72 met inclusion criteria.
  • Prevalence of databases: 65 methylomic, 59 transcriptomic, 41 proteomic, 42 metabolomic, 22 microbiomic.
  • UK BioBank identified as a comprehensive panomic resource.

Conclusions:

  • Panomic analyses benefit from large sample sizes and long follow-ups for statistical power.
  • Database completeness is vital for handling biological variability.
  • While UK BioBank is a leading resource, other databases serve specific research designs.