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Participatory Design of a Clinical Trial Eligibility Criteria Simplification Method
Yilu Fang1, Jae Hyun Kim1, Betina Ross Idnay2,3
1Department of Biomedical Informatics.
Abstract:
Clinical trial eligibility criteria are important for selecting the right participants for clinical trials. However, they are often complex and not computable. This paper presents the participatory design of a human-computer collaboration method for criteria simplification that includes natural language processing followed by user-centered eligibility criteria simplification. A case study on the ARCADIA trial shows how criteria were simplified for structured database querying by clinical researchers and identifies rules for criteria simplification and concept normalization.
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