Related Experiment Video

Updated: Nov 4, 2025

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
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A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors

Published on: June 8, 2022

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The Journey from Two-Step to Multi-Step Phosphorelay Signaling Systems

Deepti Singh1, Priyanka Gupta1, Sneh Lata Singla-Pareek1

  • 11Stress Physiology and Molecular Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India; 2Plant Stress Biology, International Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India; 3The UWA Institute of Agriculture, The University of Western Australia, Perth WA 6001, Australia; 4National Agri-Food Biotechnology Institute, Punjab, Ajitgarh 140306, India.

Current Genomics
|May 28, 2021
PubMed
Summary

Two-component signaling (TCS) systems evolved from simple prokaryotic two-step phosphorelays (TSP) to complex eukaryotic multi-step phosphorelays (MSP). This evolutionary journey, marked by structural changes in TCS components, informs crop improvement strategies.

Keywords:
Two-component systemhistidine kinaseshistidine-containing phosphotransfer proteinsmulti-step phosphorelayresponse regulatorstwo-step phosphorelay

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