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Published on: March 15, 2020
A Case of Refractory Esophageal Ulcer Caused by Radiotherapy for Hepatocellular Carcinoma
Kazu Hamada1,2, Tohru Itoh2, Ken Kawaura2
1Department of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Abstract:
A 77-year-old man who underwent radiotherapy for hepatocellular carcinoma 6 months prior consulted for esophageal obstruction. Esophagogastroduodenoscopy revealed an esophageal ulcer caused by radiotherapy for hepatocellular carcinoma. He was treated with dietary counseling and vonoprazan. After 9 months, the ulcer improved but a moderate stenosis remained. Several factors such as high fraction size, history of chemotherapy, and stress associated with food intake might involve in the development of a radiation-associated ulcer. Opportunities to choose radiotherapy for hepatocellular carcinoma may increase, so we hypothesize that esophageal ulcers might be a complication that should be noted associated with this therapy.
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